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39 Demonstrating the physiological basis of the life-threatening conditions hypothermia, hyperthermia and malignant-hyperthermia using the high-fidelity human patient simulator (HPS)
  1. JA Gibb,
  2. A Vasudev,
  3. L Day,
  4. ZJ Palmer,
  5. RJ Helyer
  1. University of Bristol, UK


Medical education and later safe practice can be enhanced by using high-fidelity manikins to simulate key physiological principles underlying clinical conditions and emergencies.1,2

Simulations of hypothermia, hyperthermia and malignant-hyperthermia, all life-threatening conditions, are currently limited. Therefore we set out to design scenarios using the CAE Human Patient Simulator (HPS, CAE Inc.) that could be valuable educational tools in the demonstration of the underlying physiology of these emergencies.

Scenarios were developed by modification of the base HPS physiological model with the aim of producing data for key variables and responses validated against published in vivo data and clinical cases. Wherever possible, a model-driven approach was maintained so that key homeostatic mechanisms remained intact.

Compared to in vivo and clinical cases, the simulations produced physiological data within in vivo target ranges determined from the literature.

These scenarios will form the basis of further development into teaching sessions for inclusion in the medical and biomedical science curricula.


  1. Harris J, Helyer R, Lloyd E. Med Educ 2011;45:1131–1162.

  2. Helyer R, Dickens P. Adv Physiol Educ 2016;40:143–144.

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