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Contributors CVV and HCG: conception of the work, acquisition and interpretation of data, drafting and critically revising, final approval and accountable for work. NM: conception of the work, interpretation of data, drafting and critically revising, final approval and accountable for work. WB and GM: conception of the work, critically revising, final approval and accountable for work.
Funding This work was supported by the James and Diana Ramsay Foundation, ‘James Ramsay Project Grant’.
Competing interests None declared.
Ethics approval Multisite ethics approval was granted by the Human Research Ethics Committee at the Queen Elizabeth Hospital (HREC/15/TQEH/76); where this approval was not recognised, local site approvals were obtained. Research Governance Approval was also obtained from all hospitals prior to site access.
Provenance and peer review Not commissioned; internally peer reviewed.
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